Metabolism and Elimination of Oxytetracycline in Hepatopancreas of Chinese Mitten Crab Eriocheir Sinensis
نویسندگان
چکیده
The kinetic profiles of Oxytetracycline (OTC) in hepatopancreas of Eriocheir sinensis was examined in this research. The results showed that after a single-dose of 40 mg/kg body weight OTC at (18±1°C) by intramuscular administration, the hepatopancreas concentration-time curve of OTC could be best described by a one-compartment model with first-order absorption and a time lag: C = 69.45×(e-0.005(t-0.0387)-e-8.195 (t0.0387)). The elimination half-life (t1/2β) was 130.71 h. It is suggested that a withdrawal time of 79.51d should be required before crabs are consumed safely.
منابع مشابه
Effect of temperature stress on the survival of juvenile Chinese mitten crab (Eriocheir sinensis)
Eriocheir sinensis, which is an important aquaculture species, belongs to the class Crustacea. To discuss the temperature tolerance of E. sinensis, the survival rates of juvenile crabs of E. sinensis were determined in this paper using a series of temperature settings (normal temperature, 25°C, 30°C, 32°C, 34°C, 35°C, 36°C, 38°C, 40 °C). The results indicated that except the normal temperature ...
متن کاملThe site of vitellogenin synthesis in Chinese mitten-handed crab Eriocheir sinensis.
The objective of this study was to investigate the synthesis site of vitellogenin in the Chinese mitten-handed crab, Eriocheir sinensis. Using the RT-PCR techniques, the cDNA fragments isolated from the ovaries of vitellogenic female crab, we found that its deduced amino acid sequence had a high identity with that from other decapods crustacean vitellogenin. This cDNA fragments were used as pro...
متن کاملMolecular Cloning and Gene Expression Analysis of the Leptin Receptor in the Chinese Mitten Crab Eriocheir sinensis
BACKGROUND Leptin is an adipocyte-derived hormone with multiple functions that regulates energy homeostasis and reproductive functions. Increased knowledge of leptin receptor function will enhance our understanding of the physiological roles of leptin in animals. METHODOLOGY/PRINCIPAL FINDINGS In the present study, a full-length leptin receptor (lepr) cDNA, consisting of 1,353 nucleotides, wa...
متن کاملThe evaluation of the three edible tissues of dead adult Chinese mitten crabs (Eriocheir sinensis) freshness in harvest season, based on the analysis of TVBN and biogenic amine
This study was carried out to evaluate the quality of the three edible tissues (muscles, hepatopancreas and gonads) of the male and female Chinese mitten crab (Eriocheir sinensis) in natural harvest season, based on total volatile base nitrogen test (TVBN) and biogenic amines analysis at intervals time of 3 h extended for 24 h during 30 °C storage (a mean ambient temperature in harvest season)....
متن کاملTranscriptomic variation of hepatopancreas reveals the energy metabolism and biological processes associated with molting in Chinese mitten crab, Eriocheir sinensis
Molting is a critical developmental process for crustaceans, yet the underlying molecular mechanism is unknown. In this study, we used RNA-Seq to investigate transcriptomic profiles of the hepatopancreas and identified differentially expressed genes at four molting stages of Chinese mitten crab (Eriocheir sinensis). A total of 97,398 transcripts were assembled, with 31,900 transcripts annotated...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2016